Tag Archives: antibiotic resistance

Umm, Bacon!

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Walmart Pork Found To Have “Superbug” Bacteria Resistant To Antibiotics

A new study published by animal-welfare group World Animal Protection has arrived at some stunning findings about pork products begin sold at Walmart.

The report , published by FoodDive, found that pork samples purchased from Walmart contained “superbug” antibiotic-resistant bacteria. 80% of samples tested from Mid-Atlantic Walmart stores were resistant to at least one antibiotic. Additionally, 37% of the bacteria in the Walmart samples were resistant to three or more classes of antibiotics.

In sum, about 27% of the resistant bacteria found on Walmart’s pork were resistant to classes categorized as Highest Priority Critically Important Antimicrobials by the World Health Organization.

160 samples of pork were tested by researchers at Texas Tech University: 80 were from Walmart and 80 were from a competing national retail chain in the Mid-Atlantic region. The samples were tested in 32 batches for E. coli, salmonella, enterococcus and listeria. Researchers said they found enterococcus in 13 batches, E. coli in 10 batches, salmonella in 6 and listeria in 3 batches.

Alesia Soltanpanah, executive director of World Animal Protection U.S., said: “The presence of multidrug-resistant bacteria on pork products illustrates the role the pork supply chain plays in the global health crisis caused by antibiotic-resistant bacteria. The fact that pork from one of the nation’s largest retailers contains bacteria resistant to antibiotics critically important to human health is particularly alarming and should raise concerns.”​

In addition to Walmart, researchers also tested pork sample from another national retail chain and also found antibiotic-resistant bacteria. However, the second batch tested did not contain two strains of multidrug-resistant bacteria in a single batch (as the Walmart batch did) and none of the samples were resistant to antibiotics considered “critically important to human health”.

The report didn’t name the second retailer, but FoodDive speculates that it is Costco, Kroger or Target, based on the report noting that the second retailer has “has committed to strengthen its animal welfare policies for its pork suppliers, including working towards a commitment to complete elimination of gestation crates for breeding sows.”

Walmart has not yet made this commitment, while Target and Costco have committed to the initiative by 2022 and Kroger by 2025. In 2016, however, Walmart partnered with IBM and Tsinghua University to track the movement of pork in China using blockchain.

As FoodDive notes, consumers are now challenging major food companies for more transparency with their manufacturing processes:

Food companies are being challenged by consumers demanding more transparency and checking manufacturing processes to make sure the products they buy reflect their values. Younger consumers responding to surveys note how they’re willing to pay premium prices for organic, natural and cruelty-free foods. Both Perdue and Tyson have attracted negative publicity involving animal welfare in recent years and had to change their practices as a result.

Antibiotic-free has become more prevalent as a label claim. Giant Food, a unit of Ahold Delhaize, debuted a private-label pork brand in 2017 with no antibiotics or hormones and 100% vegetarian-fed. And major poultry producers such as Tyson Foods, Pilgrim’s Pride and Perdue have committed to reducing or removing antibiotics from their chicken.

Soltanpanah said the WAP was in contact with Walmart about the results but that the company was “not responsive” to the concerns. Walmart has not acknowledged the problem as of November 26. 

These antibiotics – called Highest Priority Critically Important Antimicrobials – are the ones where there are few, or sometimes no, alternatives to treat people with serious infections. The Food and Agriculture Organization of the United Nations has said “antimicrobial resistance poses a serious threat to the safety and quality of feed and food, especially in food-producing animals.”

The Centers for Disease Control calls antibiotic resistance “one of the biggest public health challenges of our time.” 

from:    https://www.zerohedge.com/health/walmart-pork-found-have-superbug-bacteria-resistant-antibiotics

Antibiotic Resistance

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Antibiotic Resistance Poses ‘Catastrophic Threat’ To Medicine, Says Britain’s Top Health Official

Reuters  |  By Kate Kelland Posted: 03/10/2013 11:10 pm EDT

By Kate Kelland

LONDON, March 11 (Reuters) – Antibiotic resistance poses a catastrophic threat to medicine and could mean patients having minor surgery risk dying from infections that can no longer be treated, Britain’s top health official said on Monday.

Sally Davies, the chief medical officer for England, said global action is needed to fight antibiotic, or antimicrobial, resistance and fill a drug “discovery void” by researching and developing new medicines to treat emerging, mutating infections.

Only a handful of new antibiotics have been developed and brought to market in the past few decades, and it is a race against time to find more, as bacterial infections increasingly evolve into “superbugs” resistant to existing drugs.

“Antimicrobial resistance poses a catastrophic threat. If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics,” Davies told reporters as she published a report on infectious disease.

“And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.”

One of the best known superbugs, MRSA, is alone estimated to kill around 19,000 people every year in the United States – far more than HIV and AIDS – and a similar number in Europe.

And others are spreading. Cases of totally drug resistant tuberculosis have appeared in recent years and a new wave of “super superbugs” with a mutation called NDM 1, which first emerged in India, has now turned up all over the world, from Britain to New Zealand.

Last year the WHO said untreatable superbug strains of gonorrhoea were spreading across the world.

Laura Piddock, a professor of microbiology at Birmingham University and director of the campaign group Antibiotic Action, welcomed Davies’ efforts to raise awareness of the problem.

“There are an increasing number of infections for which there are virtually no therapeutic options, and we desperately need new discovery, research and development,” she said.

Davies called on governments and organisations across the world, including the World Health Organisation and the G8, to take the threat seriously and work to encourage more innovation and investment into the development of antibiotics.

“Over the past two decades there has been a discovery void around antibiotics, meaning diseases have evolved faster than the drugs to treat them,” she said.

Davies called for more cooperation between the healthcare and pharmaceutical industries to preserve the existing arsenal of antibiotics, and more focus on developing new ones.

Increasing surveillance to keep track of drug-resistant superbugs, prescribing fewer antibiotics and making sure they are only prescribed when needed, and ensuring better hygiene to keep infections to a minimum were equally important, she said.

Nigel Brown, president of the Society for General Microbiology, agreed the issues demanded urgent action and said its members would work hard to better understand infectious diseases, reduce transmission of antibiotic resistance, and help develop new antibiotics.

“The techniques of microbiology and new developments such as synthetic biology will be crucial in achieving this,” he said. (Editing by Jason Webb)

from:    http://www.huffingtonpost.com/2013/03/10/antibiotic-resistance-catastrophic-threat_n_2850651.html?ir=Healthy+Living

Treating Wounds with Honey

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Honey Could Be Effective at Treating and Preventing Wound Infections

ScienceDaily (Jan. 31, 2012) — Manuka honey could help clear chronic wound infections and even prevent them from developing in the first place, according to a new study published in Microbiology.The findings provide further evidence for the clinical use of manuka honey to treat bacterial infections in the face of growing antibiotic resistance.

Streptococcus pyogenes is a normal skin bacterium that is frequently associated with chronic (non-healing) wounds. Bacteria that infect wounds can clump together forming ‘biofilms’, which form a barrier to drugs and promotes chronic infection. Researchers at Cardiff Metropolitan University have shown that manuka honey can not only destroy fully-formed S. pyogenes biofilms in vitro but also prevent the bacteria initially binding to components of wound tissue.

Honey has long been acknowledged for its antimicrobial properties. Traditional remedies containing honey were used in the topical treatment of wounds by diverse ancient civilisations. Manuka honey is derived from nectar collected by honey bees foraging on the manuka tree found growing in New Zealand and parts of Australia. It is included in modern licensed wound-care products around the world. Manuka honey has been reported to inhibit more than 80 species of bacteria, yet the antimicrobial properties of honey have not yet been fully exploited by modern medicine as its mechanisms of action are not fully understood.

Wounds that are infected with S. pyogenes often fail to respond to treatment. This is largely due to the development of biofilms which may be difficult for antibiotics to penetrate — in addition to problems of antibiotic resistance. The results of the study showed that very small concentrations of honey prevented the start of biofilm development and that treating established biofilms grown in Petri dishes with honey for 2 hours killed up to 85% of bacteria within them.

The Cardiff team are working towards providing molecular explanations for the antibacterial action of honey. The latest study reveals that honey can disrupt the interaction between S. pyogenes and the human protein fibronectin, which is displayed on the surface of damaged cells. “Molecules on the surface of the bacteria latch onto human fibronectin, anchoring the bacteria to the cell. This allows infection to proceed and biofilms to develop,” explained Dr Sarah Maddocks who led the study. “We found that honey reduced the expression of these bacterial surface proteins, inhibiting binding to human fibronectin, therefore making biofilm formation less likely. This is a feasible mechanism by which manuka honey minimizes the initiation of acute wound infections and also the establishment of chronic infections.

Ongoing work in Dr Maddocks’ lab is investigating other wound-associated bacteria including Pseudomonas aeruginosa and meticillin-resistant Staphylococcus aureus (MRSA). Manuka honey has also been shown to be effective at killing these bacteria. “There is an urgent need to find innovative and effective ways of controlling wound infections that are unlikely to contribute to increased antimicrobial resistance. No instances of honey-resistant bacteria have been reported to date, or seem likely,” said Dr Maddocks. “Applying antibacterial agents directly to the skin to clear bacteria from wounds is cheaper than systemic antibiotics and may well complement antibiotic therapy in the future. This is significant as chronic wounds account for up to 4% of health care expenses in the developed world.

from:    http://www.sciencedaily.com/releases/2012/01/120131205919.htm